There'll be a little less power, maybe a little warmer, and the amp will be a little bit 'slower' in terms of response. I prefer the tube sound, but it's a taste thing.
If it's properly biased now, plugging in a pair of tubes won't hurt anything. It'll run a little cold compared to where it is now, which might not sound the best (or, it might sound just fine), but that's it. All voltages in the audio circuit will come down a bit.