For guitar, I like my Sentura II. Some don't like the distortion from the Sunn tube amps, and I can understand why. It's bright and crunchy, rather like Keith Richards' tone on "Jumping Jack Flash". However, I find that it takes pedals well, and the Mid Boost switch changes the tone a lot, making the distortion much smoother. So for me, the Mid Boost switch is a must for guitar.
For bass, I like them all. The 200S, Sentura II and Model T all sound great, though not the same.
As far as speakers go, again, they're all different, and you'd have to try some out to find the one(s) that give you what you want.