if the screech has a rythym to it (tuh, tuh, tuh, tuh......) check for a small tube that has gone lame. you call that "motorboating."
if the screech is like a siren that gets a little louder when it goes into full howl mode, the bias is incorrect on the output stage. that could be a mis-adjusted potentiometer or a bad solder joint in the bias circuit. you really need to carefully dial in the amp when it's re-tubed. it's not really cool to indiscriminately plug tubes into different amps without checking voltages and dialing things in.
time to bust out the old simpson meter and plastic wand.
best regards, tube