alright, I'll start this off by saying that while the back says you can run the coliseums at 2 ohms, 4 is probably as low as you should go so as to maintain its lifespan.
now I will try to explain the way ohms work in relation to cabs and amps:
cabs come in three main impedances, 16, 8, and 4 ohms
when you combine two cabinets, you are putting them in parallel 99 times out of 100
this means two 16 ohm cabinets will become 8 total ohms to the amp, 8 becomes 4, 4 becomes 2
when you use odd numbers(other than 1) or mismatch impedances between 2 cabs you have some nice fractional ohm calculations, which I'm sure joe or edbass would gladly post for you, I'll just stick to the basics.
with solid state amplifiers like the coliseum, it isn't necessary to have any particular ohm load, as long as it is above the minumum of 2 or 4 ohms. however the higher you go impedance wise, the lower your output wattage will be.
I think it's been said that at 4 ohms the coliseum bass puts out in the neighborhood of 150 watts, I'm not really sure.
so to sum it up, if you got a 1x15 and a 4x10 that were both 8 ohms, you'd be fine to use them both