I think tube amps are pretty forgiving of impedance mismatches, and the rule of thumb seems to be that a 100% mismatch will be tolerated by most amps. Obviously, as this thread has touched on the actual load the output stage at any given time fluctuates significantly as is illustrated by the use of the term “nominal” in front of speaker rating impedance, so that type of tolerance is pretty much required for a tube amp to function.
So I suppose by that 100% logic, while without question a proper impedance match is optimum if forced into a guessing game with an unknown cabinet, going in the middle would seem the best bet.
The big no-no is an open output. Leo Fender’s amps had jacks that defaulted to a dead short if they were empty, so I suppose at least he thought that 0 ohms were safer than infinity ohms.
As arenavore suggests I personally carry a multimeter in my gig bag with my rig cables, along with a flashlight, tool kit, soldering iron, etc. I’ve only had a handful of emergency situations arise in the past decades but when they do it saves a whole lot of frustration and cursing.